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Nutrient
Drug-Nutrient Depletion Research

Your Statin Lowers Cholesterol. It Also Crushes Nutrients.

Over 200 peer-reviewed studies show that statins can interact with critical nutrients your body depends on, leading to health impacts that are often overlooked.

40M+

Americans take a statin every day

%

of statin users report muscle pain or weakness

5

critical nutrients shown to be impacted by statins

Did You Know Statins Can Impact

5 Critical Nutrients

Research shows statins can interfere with your body's ability to
produce or absorb essential nutrients over time.

CoQ10

CoQ10

Coenzyme Q10

Statins block the same pathway your body uses to produce CoQ10, a molecule essential for cellular energy in your muscles and heart.

Linked to muscle pain, fatigue, and weakness

Vitamin D3

Vitamin D3

Vitamin D3

Statin therapy is associated with lower vitamin D levels, which plays a critical role in musculoskeletal function.

Linked to bone weakness and muscle symptoms

Vitamin K2

Vitamin K2

Vitamin K2

Statins may interfere with vitamin K2-dependent proteins that direct calcium away from arteries and into bones.

Linked to arterial calcification risk

Magnesium

Magnesium

Magnesium Malate

Statin use can affect magnesium levels, which supports over 300 enzymatic processes including cholesterol metabolism.

Linked to cramps, fatigue, and irregular heartbeat

Vitamin E

Vitamin E

Vitamin E + Mixed Tocopherols

Statins may reduce antioxidant protection against LDL oxidation, increasing the need for vitamin E.

Linked to increased oxidative stress

Designed for all statins, including:

Atorvastatin
Lipitor
Rosuvastatin
Simvastatin
Pravastatin
Lovastatin
Pitavastatin
Livalo
Zypitamag
Fluvastatin
Altoprev
Lescol XL

The Problem is Hidden in Plain Sight

Statins are effective at lowering cholesterol, but they also block the mevalonate pathway — the same pathway your body uses to produce CoQ10 and other vital nutrients.

Common Statin Side Effects

Many of the most common side effects are directly linked to nutrient depletion:

  • Muscle pain & weakness
  • Chronic fatigue
  • Brain fog & memory issues
  • Joint pain
  • Leg cramps
  • Increased blood sugar
Antidote Statin Support

Antidote Support Formula

Pharmacist-formulated to replenish what your statin depletes:

  • CoQ10 to restore cellular energy production
  • Vitamin D3 for musculoskeletal support
  • Vitamin K2 to direct calcium properly
  • Magnesium Malate for muscle function
  • Vitamin E for antioxidant defense

Formulated to Replenish What Statins Deplete

One capsule a day. Third-Party Tested. Pharmacist formulated.

HSA/FSA Eligible
Rx Not Required
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ST01

Statin Support

4.8

Daily targeted nutrient support, formulated for people taking statins.

$59.99

30-day supply delivered monthly

Free Shipping. Pause or cancel anytime.

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Clinicians Choice

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Medications Supported:

Atorvastatin
Lipitor
Rosuvastatin
Simvastatin
Pravastatin
Lovastatin
Pitavastatin
Livalo
Zypitamag
Fluvastatin
Altoprev
Lescol XL
Supports:
+11

Clinical Ingredients:

Coenzyme Q10
Coenzyme Q10
200 mg
(as ubiquinone)

Clinical research demonstrates statin therapy reduces CoQ10 levels, a nutrient critical to cellular energy production and antioxidant defense in high-energy tissues such as muscles and the heart.

Vitamin D3
Vitamin D3
25 mcg
(as cholecalciferol from lichen)

Vitamin D3 is essential for musculoskeletal function. Clinical observations link deficiency to statin-associated muscle symptoms. Plant-based D3 is used for its stability and consistency.

Vitamin K2
Vitamin K2
90 mcg
(as menaquinone-7 (MK-7))

Vitamin K2 regulates calcium placement by directing calcium where it belongs when vitamin D is present. MK-7 is selected for its clinically validated superiority in this process.

Magnesium Malate
Magnesium Malate
30 mg
(as Albion® di-magnesium malate)

Magnesium supports statin-affected cholesterol metabolism and muscle function. Albion® Di-Magnesium Malate is selected for its ability to target muscle fatigue and aches.

R-Alpha Lipoic Acid
R-Alpha Lipoic Acid
50 mg
(as Bio-Enhanced® Na-RALA sodium R-lipoate)

Statin therapy can affect oxidative stress pathways, where alpha-lipoic acid supports. Bio-Enhanced® R-ALA has improved bioavailability, stability, and solubility over standard alpha-lipoic acid.

Vitamin E + Mixed Tocopherols
Vitamin E + Mixed Tocopherols
20 mg
(as d-alpha tocopherol + mixed tocopherols)

Vitamin E supports antioxidant protection against LDL oxidation, as statin therapy may attenuate aspects of oxidative defense. Mixed tocopherols provide broader antioxidant coverage.

AbsorbEase™

AbsorbEase™ is our proprietary delivery system developed to enhance nutrient absorption.

Pill

How to Use:

Take 1 capsule daily with food, at the same time as your medication.

The Antidote Standard™

Antidote Standards

FREE OF 9 MAJOR ALLERGENS

30-Day Guarantee

Request a refund within 30 days of your order delivery for your money back.

Free Shipping

US orders ship within 1-2 business days. Limited international shipping.

Flexible Plans

Reschedule your deliveries or cancel your subscription any time.

Commonly Taken Alongside:
Lisinopril Support
Lisinopril Support
Lisinopril Support
Once Daily Capsule
Aspirin Support
Aspirin Support
Aspirin Support
Once Daily Capsule
Amlodipine Support
Amlodipine Support
Amlodipine Support
Once Daily Capsule
Omeprazole Support
Omeprazole Support
Omeprazole Support
Once Daily Capsule
HCTZ Support
HCTZ Support
HCTZ Support
Once Daily Capsule
Metformin Support
Metformin Support
Metformin Support
Once Daily Capsule

Questions, answered.

Yes. Antidote formulas were developed to be used together, with ingredient selection and nutrient overlap carefully considered across all products. Most people choose to take more than one formula as part of their routine. As always, we recommend reviewing your supplement use with your healthcare provider.

Everyone’s body responds differently. Some people may notice changes within a few weeks, while others may require more consistent use over time. Because Antidote formulas support nutrient repletion rather than immediate effects, results are often gradual. We recommend consistent daily use for sustained support.

While most people notice symptoms associated with low nutrients, it can vary and isn't always intuitive. Blood testing is the most accurate way to evaluate nutrient levels. A healthcare provider can help interpret labs and determine whether supplementation makes sense.

Got More Questions?

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4.8 Stars
Start Feeling Better
on Your Medication

Exactly what I was missing!

I’ve been using Antidote for a few weeks now and already feel less fatigued and achey. I love that it’s just one pill per day!

Sarah P.

Easy addition to my routine.

Had no idea my medication was depleting so many things, but I’m excited to to have this product in my daily routine.

David M.

Thoughtfully Designed!

I was having daily cramps before I started taking these nutrients! I am excited to try a second formula too since they work well together.

Ashley S.