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Nutrient
Drug-Nutrient Depletion Research

Taking Birth Control? Don't Overlook This.

Whether you’re on the pill, a hormonal IUD, or a transdermal patch — research shows these contraceptives can quietly deplete key nutrients your body needs to feel its best.

47M+

women in the U.S. use some form of contraception

%

of hormonal contraceptive users report mood or energy changes

11

essential nutrients shown to be impacted by birth control

Did You Know Birth Control Can Impact

11 Essential Nutrients

Research shows hormonal contraceptives — including pills, IUDs, and patches — can interfere with your body's ability to absorb and retain essential nutrients over time.

Folate

Folate

Quatrefolic® 5-MTHF

Folate levels decline with birth control use — a concern for red blood cell production, neurological integrity, and overall cellular health.

Linked to fatigue, brain fog, and low mood

Vitamin B12

Vitamin B12

Methylcobalamin

B12 levels are consistently impacted by long-term hormonal contraceptive use, affecting energy production and neurological function.

Linked to fatigue and cognitive difficulties

Vitamin B6

Vitamin B6

Dual-Form P-5-P + Pyridoxine

B6 depletion is commonly observed with hormonal contraceptive use, directly affecting mood regulation and neurotransmitter balance.

Linked to mood swings and irritability

Magnesium

Magnesium

TRAACS® Magnesium Bisglycinate

Magnesium availability can be reduced with hormonal contraceptive use, impacting daily energy, stress response, and sleep quality.

Linked to anxiety, cramps, and poor sleep

Zinc

Zinc

TRAACS® Zinc Bisglycinate

Zinc levels have been shown to be lower with hormonal contraceptive use, affecting immune balance, skin clarity, and tissue repair.

Linked to breakouts and weakened immunity

Vitamin C

Vitamin C

Ascorbic Acid

Vitamin C levels within immune cells are lower with contraceptive use, weakening antioxidant defense and cellular protection.

Linked to lowered immune resilience

Riboflavin

Riboflavin

Riboflavin-5'-Phosphate (B2)

Riboflavin activity is reduced with hormonal contraceptive use, impacting the activation of other B vitamins and neurological function.

Linked to headaches and low energy

Designed for pills, IUDs, and patches, including:

Sprintec
Junel Fe
Apri
Lo Loestrin Fe
Mirena
Kyleena
Camila
Slynd
Nora-BE
Opill
Liletta
Skyla
Estarylla
Vienva
Twirla
Aviane

The Side Effects No One Talks About

Birth control is life-changing for millions of women — but the hormonal shifts it creates can quietly deplete key nutrients, leading to symptoms that often get dismissed.

Common Birth Control Side Effects

Many of the most common side effects are directly linked to nutrient depletion:

  • Mood swings & irritability
  • Fatigue & low energy
  • Brain fog & difficulty concentrating
  • Breakouts & skin changes
  • Weakened immune response
  • Headaches & migraines
Antidote Birth Control Support

Antidote Support Formula

Pharmacist-formulated to replenish what your birth control depletes:

  • Folate (Quatrefolic®) for cellular health & methylation
  • B12 + B6 for mood & neurological support
  • Magnesium for energy & stress resilience
  • Zinc for skin clarity & immune balance
  • Vitamin C + E + Selenium for antioxidant defense

Formulated to Replenish What Birth Control Depletes

One capsule a day. Third-Party Tested. Pharmacist formulated.

HSA/FSA Eligible
Rx Not Required
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BC01

Birth Control Support

4.8

Daily targeted nutrient support, formulated for women taking birth control.

$59.99

30-day supply every 4 weeks

30-day risk-free guarantee
Pause or cancel anytime
Free US Shipping
HSA/FSA Eligible withTruemed
Limited Inventory
Due to high demand, limited inventory is available.
<14% Available86% Reserved

Your med's new

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Clinicians Choice

Clinicians share this on FrontrowMD

Medications Supported:

Sprintec
Norethindrone
Mirena
Norgestimate
Junel Fe
Lo Loestrin Fe
Kyleena
Desogestrel
Liletta
Skyla
Microgestin Fe
Estarylla
Vienva
Aviane
Lutera
Norelgestromin
Tri-Lo-Estarylla
Seasonique
Norgestrel
Twirla
Portia
Levora
Mono-Linyah
Camrese
Jolessa
Ashlyna
Daysee
Quasense
Introvale
Simpesse
Amethyst
Balcoltra
Taytulla
Tyblume
Quartette
Supports:
+34

Clinical Ingredients:

Folate
Folate
340 mcg DFE
(as Quatrefolic® 5-MTHF)

Clinical research shows folate levels decline with birth control use, a concern given folate's role in red blood cell production and neurological integrity. Quatrefolic® is selected for its clinically proven bioavailability.

Vitamin B12
Vitamin B12
400 mcg
(as methylcobalamin)

B12 levels have consistently been shown to be impacted by long-term oral contraceptive use. Methylated B12 is the most bioavailable form ensuring proper uptake.

Dual-Form Vitamin B6
Dual-Form Vitamin B6
25 mg
(pyridoxal-5′-phosphate + pyridoxine hydrochloride)

B6 depletion is often observed with oral contraceptive use, affecting mood regulation and pathways linked to blood clot risk. Combining both active (P-5-P) and reserve forms ensures maximum uptake.

Magnesium Glycinate
Magnesium Glycinate
50 mg
(as Albion® magnesium bisglycinate chelate)

Magnesium availability can be reduced with OC use, affecting daily energy and stress response. Albion® Glycinate is selected for its clinically validated TRAACS® chelation and gastrointestinal tolerability.

Zinc Glycinate
Zinc Glycinate
12.5 mg
(as Albion® zinc bisglycinate chelate)

Zinc levels have been shown to be lower with oral contraceptive use, a concern given zinc’s role in immune balance and skin health. Albion® is selected for its clinically validated TRAACS® chelation.

Riboflavin (Vitamin B2)
Riboflavin (Vitamin B2)
15 mg
(as riboflavin-5'-phosphate)

Riboflavin activity is reduced with oral contraceptive use, a concern given its role in activating other B vitamins and supporting neurological function. R-5-P is the most active form of B2, ensuring absorption.

Vitamin C
Vitamin C
50 mg
(as ascorbic acid from tapioca)

Vitamin C levels within immune cells are lower with oral contraceptive use, affecting antioxidant defense and cellular protection. Ascorbic acid is used for direct, reliable nutrient uptake.

Vitamin E + Mixed Tocopherols
Vitamin E + Mixed Tocopherols
40 mg
(as d-alpha tocopherol + mixed tocopherols)

Vitamin E demand may increase with oral contraceptive use due to heightened oxidative stress affecting cellular membranes. Mixed tocopherols provide broader antioxidant coverage.

Selenium Glycinate
Selenium Glycinate
100 mcg
(as Albion® selenium glycinate)

Selenium status may be affected with oral contraceptive use, impacting antioxidant and thyroid-related function. Albion® Selenium Glycinate is selected for its clinically validated chelation.

Thiamine (Vitamin B1)
Thiamine (Vitamin B1)
25 mg
(as thiamine hydrochloride)

B1 levels may be affected with oral contraceptive use, impacting energy and ability to focus. Thiamine hydrochloride is selected for reliable daily replenishment.

L-Tyrosine
L-Tyrosine
50 mg

L-Tyrosine has been shown to be significantly lower in women using oral contraceptives, a concern given its role as a precursor to norepinephrine involved in mood regulation.

AbsorbEase™

AbsorbEase™ is our proprietary delivery system developed to enhance nutrient absorption.

Pill

How to Use:

Take 1 capsule daily with food, in the AM.

The Antidote Standard™

Antidote Standards

FREE OF 9 MAJOR ALLERGENS

30-Day Guarantee

Request a refund within 30 days of your order delivery for your money back.

Free Shipping

US orders ship within 1-2 business days. Limited international shipping.

Flexible Plans

Reschedule your deliveries or cancel your subscription any time.

Commonly Taken Alongside:
Sertraline Support
Sertraline Support
Sertraline Support
Once Daily Capsule
Metformin Support
Metformin Support
Metformin Support
Once Daily Capsule
Fluoxetine Support
Fluoxetine Support
Fluoxetine Support
Once Daily Capsule
Omeprazole Support
Omeprazole Support
Omeprazole Support
Once Daily Capsule
Statin Support
Statin Support
Statin Support
Once Daily Capsule

Questions, answered.

Yes. Antidote formulas were developed to be used together, with ingredient selection and nutrient overlap carefully considered across all products. Most people choose to take more than one formula as part of their routine. As always, we recommend reviewing your supplement use with your healthcare provider.

Everyone’s body responds differently. Some people may notice changes within a few weeks, while others may require more consistent use over time. Because Antidote formulas support nutrient repletion rather than immediate effects, results are often gradual. We recommend consistent daily use for sustained support.

While most people notice symptoms associated with low nutrients, it can vary and isn't always intuitive. Blood testing is the most accurate way to evaluate nutrient levels. A healthcare provider can help interpret labs and determine whether supplementation makes sense.

Got More Questions?

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4.8 Stars
Start Feeling Better
on Your Medication

Exactly what I was missing!

I’ve been using Antidote for a few weeks now and already feel less fatigued and achey. I love that it’s just one pill per day!

Sarah P.

Easy addition to my routine.

Had no idea my medication was depleting so many things, but I’m excited to to have this product in my daily routine.

David M.

Thoughtfully Designed!

I was having daily cramps before I started taking these nutrients! I am excited to try a second formula too since they work well together.

Ashley S.